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CancerSafeScore
CancerSafeScore
is a blood test that measures 10 tumor markers
in women and 11 tumor markers in men. The test
was developed by CancerSafe in Switzerland and
France. The purpose of the test is to discover
cancers early, when the cure rate is highest.
Cancer
is the second leading cause of death after cardiovascular
disease. There are many different kinds of cancer,
and each kind may produce molecules that enter
the blood stream. Usually, the number of molecules
is proportional to the size of the cancer, or
tumor mass. This is why the molecules are referred
to as tumor markers.
Traditionally,
a small number of tumor markers have been used
to monitor response to treatment for an existing
cancer. Over the past decade, many new markers
have been discovered. In the US, only 4 of the
markers in the CancerSafeScore panel are routinely
measured. The other markers are being used at
advanced cancer centers in the US or in cancer
centers outside the US. CancerSafeScore combines
all of these markers into a single test.
By
using a broad spectrum of markers, CancerSafeScore
increases the likelihood of an accurate diagnosis.
For example, breast cancer can cause elevations
of three tumor markers, while lung cancer can
cause elevations of five tumor markers. When
we
measure several markers for a specific cancer,
the likelihood of early diagnosis is increased
while the likelihood of a false positive reading
is decreased. Each cancer has a pattern of markers
associated with it. The pathologists who read
the results base their interpretations on the
tumor marker pattern. The pathologists have 20
years of experience with tumor markers, and are
affiliated with the best known private cancer
clinic in France.
The
following table shows the cancers that can be
detected with CancerSafeScore, and the markers
associated with each of the cancers:
|
Type of Cancer
|
Markers Associated with this Cancer
|
|
Bladder
|
TPA,
CEA, Cyfra 21-1
|
|
Breast
|
CA15-3,
CEA, Cyfra 21-1
|
|
Colorectal
|
CEA, CA 19-9, CA 125
|
|
Esophagus
|
CEA, Cyfra 21-1
|
|
Liver
|
AFP,
CEA
|
|
Lung
|
NSE, Cyfra 21-1, CEA, CA 125, CA 19-9
|
|
Ovary
|
CEA, CA 125, CA 19-9, AFP, BHCG
|
|
Pancreas
|
CEA, CA 19-9, CA 72-4
|
|
Prostate
|
PSA,
FPSA and ratio
|
|
Stomach
|
CA
72-4, CEA, CA 19-9
|
|
Testicle
|
BHCG,
AFP
|
|
Thyroid
|
CEA,
NSE
|
|
Uterine
|
SCC, Cyfra 21-1, CEA, CA 19-9, CA 125
|
CancerSafeScore
is obtained through a blood specimen drawn
in
the LifeScore laboratory. The blood is centrifuged
and the serum separated from the red blood cells.
The serum is frozen, and overnight mailed to
the
Chaperon-Tarbouriech Laboratory in Avignon, France.
Results are transmitted to LifeScore within one
to two days. The client receives an in-depth
report
that includes an interpretation of the results
and information about the various markers. Should
the results be abnormal, appropriate recommendations
are provided. In effect, each test includes the
equivalent of a consult with the CancerSafe physicians.
The
recommended age for obtaining the test is 50
or
older, unless there are specific risk factors
that may place an individual at risk earlier
in
their lives. Thereafter, it is recommended that
the test be performed once each year. Over time,
results are cumulatively reported with graphs,
so that trends can easily be identified.
For
the first time, CancerSafeScore offers a comprehensive,
convenient, affordable and non-invasive test
for
the early detection of 13 cancers. One in three
people in America will develop cancer over
the
course of their lives. CancerSafeScore will increase
the likelihood of finding the cancer as
early as possible, when treatment will usually
be the most effective.
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